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Segmentation of the Alzheimer's therapeutic target BACE-1

This is a GIF image of the 46 segments made of the Alzheimer's therapeutic target BACE-1 (PDB accession code: 6eqm). The larger red "blobs" indicate the volume of the active site. The other colors are based on a pharmacophore model in which violet = HBond acceptor, orange = HBond donor, lite blue = aromatic, green = polar, and gray = hydrophobic.


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